ACP Journal Club
ACP Journal Club surveys over 200 peer-reviewed medical journals to bring physicians summaries of the evidence-based clinical information necessary to practice good medicine; requires subscription for non-members of the American College of Physicians.
Bandolier
Bandolier is produced monthly in Oxford for the NHS R&D Directorate. It contains bullet points (hence its title) of evidence-based medicine. Internet access is free. Other useful information provided includes information on pain research and an easy-to-use NNT calculator. The site also provides links to other good websites such as the Oxford Pain Relief website which has a database of NNTs for various analgesics.
Best BETS
Best Evidence Topics (BETs) were developed in the Emergency Department of Manchester Royal Infirmary, UK, to provide rapid evidence-based answers to real-life clinical questions, using a systematic approach to reviewing the literature. BETs take into account the shortcomings of much current evidence, allowing physicians to make the best of what there is. This site allows you to browse or search a large database of BETs as well as allowing readers to submit their own.
Center for Clinical Effectiveness
This site is operated through the Monash Medical Center in Australia. The objective is to enhance patient outcomes through the clinical application of the best available evidence about treatments. The site offers users full evidence reports on a number of topics. It also provides good links to similar websites, which are separated by category, making the site easy to use. Finally, the Center has a section of its website where you can actually submit clinical questions regarding patients and they will research the topic of interest and respond directly to your question.
Centre for Evidence-Based Medicine
The NHS R&D CEBM was established in Oxford as the first of several centres around the UK whose goal is to promote evidence-based health care and to provide support and resources to others trying to practice and teach EBM. The website includes an EBM Toolbox with various tools for practising and teaching EBM, the CATMaker (a software programme allowing the user to create 1-page summaries of the evidence), a calendar of EBM events, and links to other EBM sites.
Centre for Evidence-Based Mental Health
The aim of the CEBMH is to promote and support the teaching and practice of evidence-based mental health care. This site provides materials to help develop skills in practising EBMH and is aimed at users trying to provide training courses and at people wanting to improve their EBMH skills by working through some online tutorials for practicing EBMH. Links to other useful resources including the full text online journal Evidence-Based Mental Health are also available resources including the full text online journal Evidence-Based Mental Health are also available from this site.
Centres for Health Evidence
The principal task of Centres of Health Evidence (CHE) is to package, disseminate, and present health knowledge in ways that facilitate its optimum use. This web site hosts the User's Guides to the Medical Literature produced by JAMA.
Clinical Assessment of the Reliability of the Examination
In an attempt to solve the problems of both small sample size and clinical applicability that are present in the clinical exam literature, an international group of investigators are trying to execute large, simple and fast studies of the accuracy and precision of various elements of the clinical examination using the Internet. This site provides all the protocols that the study group is involved with and instructions on how to join the group. Protocol development, investigator recruitment, patient enrollment and date entry are all done via the Internet.
Clinical Decision Rules
This is a site maintained at The Samuel Bronfman Department of Medicine provides clinicians with valid clinical decision rules. Clinicians just need to fill in the information for their patients and then it will derive the post-test probabilities.
Clinical Evidence
Clinical evidence is a six monthly, updated compendium of evidence on the effects of common clinical interventions, published by the BMJ Publishing Group. It provides a concise account of the current state of knowledge, ignorance and uncertainty about the prevention and treatment of a wide range of clinical conditions based on thorough searches of the literature. It summarises the best available evidence and focuses on the effects of preventative and therapeutic interventions as demonstrated by randomised trials and systematic reviews of such trials.
Clinical Examination Research Interest Group
This useful site outlines the activities of the Clinical Examination Research Interest Group which includes the Rational Clinical Examination Series published in JAMA. This is a series of more than 30 systematic reviews which address the precision and accuracy of various elements of the clinical examination. The site provides a complete listing of all of these articles and links to the relevant PubMed abstracts. It also provides a search engine for searching PubMed and Bedside Diagnosis for literature about the clinical examination.
The CONSORT Statement
CONSORT, which stands for Consolidated Standards of Reporting Trials, encompasses various initiatives developed by the CONSORT Group to improve the reporting of randomized controlled trials (RCTs). This website contains the current definitive version of the CONSORT Statement and up-to-date information on extensions.
eMedicine (from WebMD)
Medscape’s continually updated clinical reference
EPIQ (Effective Practice, Informatics & Quality Improvement)
EPIQ (Effective Practice, Informatics & Quality Improvement) was established to support effective evidence-based practice, health informatics and quality improvement initiatives in the health and disability support sectors. EPIQ is a collaboration of academics, clinicians and other health sector professionals and replaces EPI (the Effective Practice Institute).
Equator Network
The EQUATOR Network is an international initiative that seeks to improve the quality of scientific publications by promoting transparent and accurate reporting of health research. The site provides reporting guidelines how to report research methods and findings depending on the design of the studies. These include guidelines for Interventional studies, Observational studies, Diagnostic accuracy studies, Systematic reviews and meta-analysis, Qualitative research, Economic evaluations, Quality improvement studies and other reporting guidelines.
Evidence-Based Medicine
Evidence-Base Medicine is a journal released every other month which alerts clinicians of important advances in general and family practice, internal medicine, surgery, psychiatry, pediatrics and obstetrics and gynecology. This is accomplished by selecting from the biomedical literature those original and review articles whose results are most likely to be true and useful. The articles are also summarised in abstracts and a commentary by a clinical expert is added. This site contains an large archive of articles organized by both category and date as well as useful links to other evidence-related websites.
Evidence-Based Mental Health
Evidence-Base Mental Health is a journal released four times a year which alerts clinicians working in the field of mental health of important and clinically relevant advances in treatment, diagnosis, aetiology, prognosis/outcome research, quality improvement, continuing education, economic evaluation and qualitative research. This is accomplished by selecting original and review articles whose results are most likely to be accurate and clinically useful. The articles are also summarised in abstracts and a commentary by a clinical expert is added. This site contains an large archive of articles organized by both category and date as well as useful links to other evidence-related websites.
Evidence-Based Nursing
Evidence-Base Nursing is a journal released four times a year which alerts practising nurses of important and clinically relevant advances in treatment, diagnosis, aetiology, prognosis/outcome research, quality improvement, continuing education, economic evaluation and qualitative research. This is accomplished by selecting original and review articles whose results are most likely to be accurate and clinically useful. The articles are also summarised in abstracts and a commentary by a clinical expert is added. This site contains an large archive of articles organized by both category and date as well as useful links to other evidence-related websites.
Evidence-Based On Call
This site provides overviews and CATs on many acute care topics and is supported by the NHS Electronic Library for Health
Evidence-Based Pediatrics
This site is a resource for evidence-based pediatrics provided through the University of Michigan. The site includes a list of CATs, a CAT template (step by step guide on how to create a CAT), guidelines for starting a journal club and links to other websites. Another feature of this site is that it provides the user with a search engine so that the user can filter through irrelevant information and find what they are looking for quite easily.
Evidence-Based Practice Centers
The Agency for Health Care Policy and Research (AHCPR) has 12 centers in the United-States for developing evidence reports and technology assessments of diagnostic and therapeutic interventions used in a variety of clinical conditions. The partners of AHCPR use the products of Evidence-Based Practice Centers to develop and implement practice guidelines and other clinical quality improvement tools. The site contains evidence reports as well as links to each of the 12 centers across the US.
Evidence Based Surgery
Developed by the Surgical Outcomes Research Centre (SOURCE) at McMaster University, this site aims to introduce members of the surgical community to the concepts of evidence-based surgery, to interest them in using an evidence-based approach in clinical practice and to reinforce the need for surgeons to get involved in surgical research. It provides a series of articles on EBM for surgeons and links to other sites such as the Centre for Minimal Access Surgery
Evidence UPDATES (from the BMJ Evidence Centre)
BMJ Group and McMaster University's Health Information Research Unit provide free access to individually tailored, current best evidence from research to support evidence-based clinical decisions. Citations (from over 150 premier clinical journals) are pre-rated for quality by research staff, then rated for clinical relevance and interest by at least 3 members of a worldwide panel of practicing physicians. The site also offers a searchable database of the best evidence from the medical literature, an email alerting system and links to selected evidence-based resources.
Evidence Update (from the Cochrane Infectious Diseases Group)
Evidence Update is a downloadable two-page (pdf) summary, of a Cochrane Systematic Review of healthcare interventions relevant to people in low-income and middle income-countries. Each Evidence Update is prepared by a member of the Effective Health Care Research Programme Consortium (EHCRPC) in collaboration with the Australasian Cochrane Centre and is updated every time a review update is published in the Cochrane Database of Systematic Reviews (part of The Cochrane Library).
Faculty of 1000 Medicine
The site offers what leaders in clinical practice and research select as the most influential articles, rate the significance of selected articles and evaluate the most important and influential articles.
Grade Working Group
The Grading of Recommendations Assessment, Development and Evaluation (short GRADE) Working Group is as an informal collaboration of people with an interest in addressing the shortcomings of present grading systems in health care. The working group has developed a common, sensible and transparent approach to grading quality of evidence and strength of recommendations. The GRADE working group's grading software GRADEpro is now available for download from a Cochrane Collaboration website.
Indian Medlars Centre
The center is set up jointly by the National Informatics center and the India Council for medical Research. It contains IndMED, a database covering prominent peer reviewed Indian biomedical journals. Database designed to provide medical professionals / researchers / students and the medical library professional quick and easy access to Indian literature as well as other useful links.
McMaster Health Information Research Unit
The goal of HIRU is to improve the effectiveness and efficiency of health care by providing innovative evidence-based information products and systems to health professionals, patients, policy makers, and the public. It is involved in a number of initiatives including being the location for: a national centre for the Cochrane Collaboration; HEALNet; an Evidence-based Practice Centre; Cancer Care Ontario and a variety of evidence-based publications.
National Guideline Clearing House
The NGC is an initiative of the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health and Human Services. It is a comprehensive database of evidence-based clinical practice guidelines and related documents.NGC offers Syntheses of selected guidelines that cover similar topic areas, and Expert Commentary on issues of interest and importance to the clinical guideline community.
National Library of Medicine's Health Services/Technology Assessment Text (HSTAT)
This site is basically a very detailed search engine. It contains holdings from the AHCPR support guidelines, the AHCPR technology assessments and reviews, ATIS (HIV/AIDS technical information), NIH Warren G. Magnuson Clinical Research Studies, NIH Consensus Development Program, PHS Guide to Clinical Preventative Services (1989) and SAMHSA/CSAT Treatment Improvement Protocol (TIP).
Netting the Evidence
The goal of this website is to provide a complete list of evidence-based practice resources that are available on the Internet. There are more than 140 listings (arranged alphabetically), each of which includes a short description of the resource with a link to it. This list is preceded by a link to "the latest articles on Evidence Based Medicine from the MEDLINE database". The website is easy to use and a search engine is provided.
NHS Centre for Reviews and Dissemination
The NHS Centre for Reviews and Dissemination (CRD) is the sibling of the UK Cochrane Centre and has the goal of producing reviews concerning the effectiveness and cost-effectiveness of healthcare interventions. It provides access to several databases including a database of structured abstracts of good quality systematic reviews (DARE) which comment on the methodological features of published reviews and summarise the author's conclusions and any implications for health practice. It also provides the full text Effective Health Care Bulletin which is a bi-monthly bulletin for decision-makers that examines the effectiveness of a variety of health care interventions. Effective Health Care bulletins are based on a systematic review and synthesis of research on the clinical effectiveness, cost-effectiveness and acceptability of health service interventions.
National Institute for Health and Clinical Excellence
The National Institute for Health and Clinical Excellence (NICE) is the independent organisation responsible for providing national guidance in the UK on the promotion of good health and the prevention and treatment of ill health. NICE produces guidance in three areas of health: public health - guidance on the promotion of good health and the prevention of ill health for those working in the NHS, local authorities and the wider public and voluntary sector; health technologies - guidance on the use of new and existing medicines, treatments and procedures within the NHS; clinical practice - guidance on the appropriate treatment and care of people with specific diseases and conditions within the NHS.
Ovid EBM
Ovid provides access to a variety of resources including bibliographic databases (such as MEDLINE, EMBASE and CINAHL); more than 300 full text journals; and other clinical information products such as Evidence Based Medicine Reviews (EBMR), some textbooks and Clinical Evidence which is a bi-annual compendium of evidence of the benefits and harms of some common clinical interventions. Ovid is fully integrated and a single search engine is used for all the databases and full text journals. Access to the various databases is purchased separately. EBMR contains material from Best Evidence (which includes the contents of ACP Journal Club and Evidence Based Medicine) and the Cochrane Database of Systematic Reviews. It combines Best Evidence and the Cochrane Database into a single, fully searchable database with links to both MEDLINE and Ovid full-text journals. Because the databases are interlinked, users can begin a search in MEDLINE and link from MEDLINE citations to the abstract and commentary for the relevant article in Best Evidence, to the full text article, and to relevant Cochrane Reviews. Alternatively, MEDLINE searches can be limited to articles retrieved from Best Evidence. Ovid EBMR is a great resource but it must be purchased separately from Journals@ovid. Ovid EBMR is updated quarterly.
Physiotherapy Evidence Database (PEDro)
PEDro is an initiative of the Centre for Evidence-Based Physiotherapy (CEBP) and has been developed to give physiotherapists and others rapid access to bibliographic details and abstracts of randomised controlled trials, and systematic reviews of randomised controlled trials, in physiotherapy. Most English-language randomised controlled trials and systematic reviews in physiotherapy are on the database. Trials and reviews in other languages are represented, but probably less comprehensively. Information is also provided on how to critically appraise the trials that have been identified. Links to other useful websites are also provided.
PubMed
PubMed is an Internet interface for MEDLINE. It is a project developed by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), located at the National Institutes of Health (NIH). It has been developed in conjunction with publishers of biomedical literature as a search tool for accessing literature citations and linking to full-text journals at Web sites of participating publishers. Using the 'Clinical Queries' feature in PubMed, you can restrict retrieval to articles that are most likely to asnwer your clinical question. This specialized search is intended for clinicians and has built-in search "filters". Four study categories--therapy, diagnosis, etiology, prognosis--are provided, and you may indicate whether you wish your search to be more sensitive (i.e., include most relevant articles but probably including some less relevant ones) or more specific (i.e. including mostly relevant articles but probably omit a few). PubMed is updated continuously as information is received from the publishers.
Resources for Practicing Evidence-Based Medicine
This site specializes in pediatric critical care (intensive care) medicine. It teaches the user how to use evidence-based medicine (e.g. how to critically appraise medical literature, how to use and calculate relevant statistics and how to use systematic reviews). The site also contains links to websites providing CATs, evidence-based medicine groups, databases/directories, journal clubs as well as teaching resources.
SumSearch
SumSearch (formerly SmartSearch) is a 'meta-searching service' that searches the following resources: A) Textbook. The default textbook to search is the Merck Manual. B) MEDLINE for review articles and editorials from high quality, general journals that have full texts available. C) National Guideline Clearinghouse from the Agency for Health Care Policy and Research (AHCPR) D) Database of Abstract of Reviews of Effectiveness (DARE) E) MEDLINE for original research. Depending of the focus requested SUMSearch will search PubMed with the highest sensitivity filters developed by Haynes et al. SUMSearch will also do focused searches depending on the type of information requested. For example, if the question being searched is one about the physical examination, SUMSearch will search the database Bedside Diagnosis.
South Asian Database of Controlled Clinical Trials
This online, free, searchable database of controlled clinical trials is maintained by the South Asian Cochrane Centre and provides access to all controlled clinical trials conducted in humans in countries in South Asia.
The Cochrane Collaboration
The Cochrane Collaboration is an international non-profit and independent organisation, dedicated to making up-to-date, accurate information about the effects of healthcare readily available worldwide. It produces and disseminates systematic reviews of healthcare interventions and promotes the search for evidence in the form of clinical trials and other studies of interventions. The major product of the Collaboration is the Cochrane Database of Systematic Reviews which is published quarterly as part of The Cochrane Library. This site also contains links to Cochrane resources for systematic review authors such as the Cochrane Handbook for Systematic Reviews,RevMan5 software and more.
The Oxford Pain Internet Site
This site is for anyone with a professional or personal interest in pain and analgesia. It is firmly based in the principles of evidence-based medicine and has pulled together systematic reviews with pain as an outcome. Accessed via Bandolier The Toronto Western Hospital - University Health Network Department of Family &Community Medicine This website provides a listing of (and links to) EBM resources with brief descriptions that are useful to family practitioners. EBM links are listed in alphabetical order to avoid ranking. Special attention is paid to the Critical Appraisal series from the Canadian Family Physician.
Trip Database
The TRIP Database searches over 75 sites of high-quality medical information. The TRIP Database gives you direct, hyperlinked access to the largest collection of 'evidence-based' material on the web as well as articles from premier on-line journals such as the BMJ, JAMA, NEJM, and many more specialist journals.
UpToDate
UpToDate is an evidence based, peer reviewed information resource that provides topic reviews that include a synthesis of the literature, the latest evidence, and specific recommendations for patient care.
Users Guide to Evidence Based Practice
Maintained by The Centre for Health Evidence, this site contains the complete set of Users' Guides, originally published as a series in the Journal of the American Medical Association (JAMA). The CHE continues to maintain the full text pre-publication version of this series on behalf of the Evidence-Based Medicine Working Group.
WHO International Clinical Trials Registry Platform
The mission of the WHO International Clinical Trials Registry Platform is to ensure that a complete view of research is accessible to all those involved in health care decision making in order to improve research transparency and will ultimately strengthen the validity and value of the scientific evidence base. The main aim of the WHO ICTRP is to facilitate the prospective registration of the WHO Trial Registration Data Set on all clinical trials, and the public accessibility of that information.
The site contains the ICTRP Search Portal that aims to provide a single point of access to information about ongoing and completed clinical trials. It provides a searchable database containing the trial registration data sets made available by data providers around the world meeting criteria for content and quality control.
The data providers for the ICTRP currently are: